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  1. Hsien-Hsien Lei, PhD on October 15th, 2009 9:02 am

    Daniel at Genetic Future will be there. Who else?

  2. [...] As part of the blog launch, HUGO is offering a free meeting registration at the HUGO Genomics and Ethics, Law and Society Symposium in Switzerland on November 1- 3. Check out this page for details. [...]

  3. [...] Annual American Society of Human Genetics Meeting in Hawaii from October 20-24, HUGO will offer complimentary HUGO memberships to readers of HUGO MATTERS and attendees of the ASHG. Just chat with a HUGO member at booth 333. [...]

  4. PATRICIA GONZALES on October 20th, 2009 5:02 am

    I cannot be at the seminar but would love to go if I were able. Please consider me for a complimentary membership. Thank you and best of wishes for your work!

  5. Hsien-Hsien Lei, PhD on October 20th, 2009 10:04 am

    Thank you for your interest, Patricia. We look forward to hearing from you again.

  6. | Avey-ation on November 12th, 2009 2:26 am

    [...] 23andMe co-founder and President of the nascent Brainstorm Research Foundation Linda Avey is blogging: The usual arrows were flying at the HUGO conference…a few, very vocal scientists seem to be quite threatened by this notion of democratizing DNA. They characterize it as “trivializing”, which simply doesn’t make sense. I just don’t agree that providing people with their genetic data, which would be virtually impossible for them to derive on their own, demeans or trivializes it. Rather, I think the research community has taken the notion of “human subject protection” way too far, to the point of unchecked paternalism (for more on this, check out Anne’s post here, And I do think the lay public is capable of understanding that what is currently known about their DNA is mostly a work-in-progress. (via Genomeweb and HUGO) [...]

  7. [...] a clear difference between them. The difference is Dr. Hsien-Hsien Lei who is the official editor of HUGO Matters and one of the best genetic bloggers in the whole blogosphere. No matter how fantastic experts [...]

  8. Edison Liu on December 9th, 2009 6:21 am

    Excellent overview of the issues. The south-to-north genetic gradient is seen throughout the Asian continent with greater diversity in the south. Moreover, the geographical and language associations of genetic groups is quite strong.

  9. Brian Ring on December 9th, 2009 3:32 pm

    Yes, the population genetics that is now feasible is very interesting. The consistent results of both papers promises that focused analyses could reveal more complex smaller scale or overlapping migration patterns, roles of family or clan networks in population dynamics, and the relations of language and dialect groups. Hopefully these papers will also encourage expanded studies encompassing more regions and subpopulations across Asia, tying the story of the Han population’s genetic geography with that of the rest of the continent.

  10. Mapping Asian Genetic Diversity « ricketyclick on December 14th, 2009 6:23 am

    [...] for self, a paper on how humans spread through Asia. Via More Words, Deeper [...]

  11. Jodell Bumatay on December 15th, 2009 5:58 pm

    I would love to discover more about this. I was raised with the information that my ancestors in the Philippines are from Tugadin, that my tribal language last name also signifies that everyone with my lastname is a blood relative. When I was thirteen, I first travelled to the Philippines with my grandparents. I noticed that some of my cousins looked like Indians from India. Also, our tribal roots are from the area on the coast of the sea of China which I know that there was trade. It would be most interesting to check genetics. My family is very tribal oriented and I am sure that one of my cousins in the Philippines would volunteer for the family genetics tests. How does one get more info?

  12. Prof P.K.Das,Haldane Chair ,Utkal University,Bhubaneswar.Orissa ,India on December 17th, 2009 12:04 pm

    Dear Dr Vikrant,
    It was heartening to read your comments.I am happy that you have raised valid anthropological questions. I would like to suggest the following for future research in the field of human genome diversity.
    1.It is generally seen that non-anthropologists generate blood samples arbitarily without tracing the geneology before drawing samples from the population
    2.The variants of caste/tribal populations are not given due importance in describing a population
    3.The ethno-history,linguistic affiliations,kinship terminogies,place name,materal cultures are never studied seriouly to show relatedness between genome diversity and cultural diversity
    4.When we say that ancient population migrted from India to China,it is essential to know whether it was from tribal stock or caste stock. This has to attested by ethno-historical and archaelogical facts.We have found out ALDH2*2 gene (Han-chineses gene) in certain section of Bonda Highlanders .What could be the explantion? Was the variant from China or emerged in the tribe independently? How do we establish in-out migration?
    5.Finally,region specific study should be undertaken as Indian popualtion is vast and diverse.Region wise Collaboartive research is a must.
    Kindly send me full copy of the paper.
    With regards

  13. Prof P.K.Das,Haldane Chair ,Utkal University,Bhubaneswar.Orissa ,India on December 17th, 2009 12:30 pm

    Dear Dr Ring,
    It is heartening to find your comments.The study of genomics of Han Chinespopulation will definitely help us in understaning the migration of Han
    Chineses people from prehistoric past to present.Recently my student Sri J
    Nayak has identified ALDH2*2 allele (Alcohol protective gene) among the most primitive tribal populations of Orissa,suggesting possible inflow of the han chinese gene to Orissan tribal populations (austroasiatic) in
    prehistoric/neolithic time.
    Please communicate views
    Prof P.K.Das

  14. Prof P.K.Das,Haldane Chair ,Utkal University,Bhubaneswar.Orissa ,India on December 25th, 2009 9:09 pm

    Dear Dr Riang,
    It is heartening to find your comments.The study of genomics of Han Chinese population will definitely help us in understanding the migration of Han Chineses people from prehistoric past to present.Recently my student Sri J. Nayak has identified ALDH2*2 allele (Alcohol protective gene) among the most primitive tribal populations of Orissa,the BOND suggesting possible inflow of the Han chinese gene to Orissan tribal populations (austroasiatic) in prehistoric/neolithic time or vice-versa. A collabotive study is needed
    Please communicate views
    With warm regards
    Prof P.K.Das

  15. Prof P.K.Das,Haldane Chair ,Utkal University,Bhubaneswar.Orissa ,India on December 25th, 2009 9:20 pm

    Dear Dr Kumar,
    Congratulation for your scientific paper.
    It was intresting to read your comments on the recent paper published
    in science.I have posted my comments on the paper.Did you receive
    that?Please let me know.
    My student Jayanta could find a East Asian gene variant ALDH2*2 in
    Bond highlanders an austroasiatic tribal group.The question is whether
    the migration was from China to India or from India to China ? We have
    to adduce evidence from language ,archaeology and cultural artifact to
    substantiate the migration.Further,as I know people collect blood
    samples without knowing the real genealogy.Even people have collected
    blood samples from market place,schools etc.Nobody raises this
    fundamental question.The genome research without anthropological
    insight is meaningless.
    We are creating a genome data bank in our lab for 62 tribal groups of
    orissa and it is in process.
    Please send the full paper so that I can send my comments.

    With best wishes as you are my frined’s student(Mohan

  16. [...] The following paragraph is cited from HUGO’s website: [...]

  17. [...] Focus: Genetics and Genomics Law (interview with @genomicslawyer ) « Előző | Következő »Berci — 2010. 02. 09. 21:41 [...]

  18. mariam on February 11th, 2010 8:42 pm

    This is the genetics ….This is the most important to have in our world the human genome organization………………..
    Its amazing ,I hope to complaete with genetic world but unfortunately I can’t ..
    this is the way to do any thing yes go ahead with the human genome ..
    Kind Regards…

  19. Pallavi Shukla on February 12th, 2010 2:45 am

    I am very much agreed to the write up Prof. Edison T Liu on “The Looming Problem of Word Limits and Scientific Publication”. The publication pattern should change in such a way that the core work can be presented in the main paper and supplementary should be short and should be used to present the additional details only.

    I could not agree more with the rationale presented by Prof. Liu, but I tend to differ on the conclusion drawn. I think if it had been a debate between brevity and clarity, it would have been easier for me to agree with him.
    Of course, clarity and comprehension cannot be compromised at the expense of brevity, but what about ambiguity and verbosity.

    I feel a research article should be clear and concise and the technical details, statistics, derivations and demographics should be described in the supplement. Referring to supplements or references may or may not distract a reader but bombarding the reader with the information that is not very relevant will certainly do. I believe reporting in a clear and concise way is as important as is generating quality data. In the absence of word limit, it is easier for a research to be redundant and verbose – two factors that can only confuse the reader.

    I however believe that the word limit should be case specific and a proper care should be given in making sure that the world limit should not curtail the relevant information. It is a difficult, but not an impossible task. It demands a balancing act and I am sure with some efforts, editorial board of Journals and the experts on the subject can arrive at a figure that will do a justice to both the writer and the reader, making sharing of scientific information faster, easier and efficient.

  20. [...] February 16, 2010 Posted by Bertalan Meskó in Slideshow, Web 2.0, genetics. trackback An interview with Trish Brown, Vice President of Clinical Affairs at DNA Direct was published on the HUGO Matters [...]

  21. Pallavi on February 19th, 2010 2:53 am

    The interview with Mr. Vorhaus is really inspiring and showed the wider career opportunities in genetics. I am also a student of genetics. Keep us updated about various career prospects in this field.

  22. [...] 10 Tips for Scientists on Blogging and Social Networking (HUGO Matters): Fantastic tips for scientists from Hsien-Hsien Lei. [...]

  23. Blair Anderson on March 4th, 2010 12:11 am

    Very interested in the book, and would love another chance to try and win it :)

  24. Khader Shameer on March 4th, 2010 1:59 am

    Good to know about this new exciting book on emerging areas in Systems Biology. Topics looks really interesting. Thanks to HUGO for innovative concept to spread the word about the book. I am excited to be part of the chance to win this. Looking forward for the result.

  25. Chris Whelan on March 4th, 2010 3:36 am

    The book looks great – I’d love to read it!

    For introductory systems biology concepts I really like “An Introduction to Systems Biology: Design Principles of Biological Circuits” by Uri Alon. Dr. Liu’s book sounds like it would present a great way to extend those concepts to medicine.

  26. Hsien-Hsien Lei, PhD on March 4th, 2010 10:12 pm

    Thanks very much for your comments!

    Systems Biology and Biomedicine is definitely where we’re headed. Glad to know there are people interested in pondering that next step!

  27. Nick Holden on March 4th, 2010 10:50 pm

    Sounds like a fascinating book, and this draw is an interesting attempt to promote it. Hope it helps to spread the word about HUGO.

  28. Hsien-Hsien Lei, PhD on March 4th, 2010 10:51 pm

    Glad to see there’s so much interest, Nick!

  29. Jill on March 5th, 2010 12:16 am

    Sounds interesting!

  30. Hsien-Hsien Lei, PhD on March 5th, 2010 12:20 am

    Thanks, Jill. It most definitely is!

  31. Dr. Bertalan Mesko on March 5th, 2010 5:24 pm

    Very interesting and nice initiative, Hsien!

  32. Hsien-Hsien Lei, PhD on March 5th, 2010 10:35 pm

    I knew you’d approve, Berci. ;)

  33. Jacob Shiach on March 5th, 2010 11:08 pm

    This book looks very interesting. I look forward to reading it.

  34. Hsien-Hsien Lei, PhD on March 5th, 2010 11:28 pm

    Thanks for participating, Jacob! I hope you will have the chance to read the book whether via us or the library.

  35. nidhan on March 6th, 2010 8:05 pm

    very interested to read the book .. i want to move into the systems biology in my post doc .. i think this book would be really helpful..

  36. Jason Bobe on March 10th, 2010 10:14 am

    “Although the Bushmen will most likely not be in attendance…”

    Don’t speak too soon! We would love to host the participants in the South African Genome Project ( and we are going to make every effort to incorporate them into the program. Would be wonderful. Fingers crossed!


  37. Dr. Bertalan Mesko on March 10th, 2010 4:23 pm

    Great interview about a really emerging field. Thank you Hsien & Keith!

  38. Pallavi Shukla on March 10th, 2010 7:53 pm

    Thanks for uploading such an informative interview showing the dynamic nature of genetics. This is really applied genetics, benefits coming to the common people.

  39. Hsien-Hsien Lei, PhD on March 10th, 2010 11:58 pm

    Bertalan and Pallavi, Thank you for your comments! More good stuff to come.

  40. Pallavi Shukla on March 11th, 2010 1:51 pm

    I like the interviw as it does not only provides the basic info about the emerging field, but also its origin, market scenario as well as pointing out that how big datas are irrevelant for the people and small and concise information by a low cost can benefit to the people. Also, the financial information for investments will be fruitful to serious investors.

  41. Pallavi Shukla on March 11th, 2010 2:15 pm

    Oh my God. I miss the chance to comment. I was always fascinated by the word “system biology” wanna have book to understand the concepts. Plz accept the comment. though its 11th march.

  42. Pallavi Shukla on March 11th, 2010 2:43 pm

    The video of Dr. Raju was nice and very informative. I am an indian student working on genetics. Get to know about the new emerging field “Personalized medicine” through this video.